HSE201 Lecture Notes - Lecture 4: Buffer Solution, Triglyceride, Phosphofructokinase

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28 Jun 2018
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4. Anaerobic Metabolism during Exercise
- Aerobic Metabolism: the dominant pathway of ATP production during most exercise situations
- Anaerobic ATP provision: provides an energy buffer when aerobic provision cannot meet ATP
demand
Supramaximal exercise
- The Wingate Anaerobic cycling test
- Expected outcomes of SE:
- A) ATP hydrolysis:
ATP + H2o --><-- ADP + Hi I Pi + energy
- B) Creating kinase reaction:
PCr + ADP + Hi --><-- Cr + ATP
- C) Adenalyate kinase reaction (a) and
myoadenyalate deaminase reaction (b)
- A: ADP + ADP --><-- ATP + AMP
- B: AMP --> IMP + NH3
- Glucose + 2NAD+ + 2ADP + Pi 2Lactate + 2NADH + 2H+ + 2ATP
- Glycogen+ 2NAD+ + 3ADP + Pi 2Lactate + 2NADH + 2H+ + 3ATP
Examination of the effects of 30s supramaximal exercise bouts
- Cycling study:
- Running study:
- Had very similar results even though diff types of exercise, by product and ammonia produced
- Phosphagen fuel:
- Glycolytic fuel:
- Adenine nucleotide pool: expecting an increase in ATP
- Purine nucleotides:
- Shows muscle tries hard to generate ATP and stop pool forming, products are something that can
get into the circulation, reducing total Adenine/Purine pool in the muscle
- 24-48 hours before get the pool back to normal after maximal exercise
- Can influence training and performance
- Total: IMP responsible for reducing pool throughout the 30s exercise
Anaerobic contributions to supramaximal exercise:
- PCr providing a lot at the beginning then lessons throughout the
time
- ATP: also falling
- Glycolysis: roughly similar throughout the bout, inaffected
- The use of glycolysis to produce lactate slows,
- Power is falling, increase in aerobic contribution
Aerobic contribution to perceived anaerobic exercise:
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Document Summary

Aerobic metabolism: the dominant pathway of atp production during most exercise situations. Anaerobic atp provision: provides an energy buffer when aerobic provision cannot meet atp demand. Atp + h2o -->

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