HNN215 Lecture Notes - Lecture 2: Antimicrobial Resistance, Aminoglycoside, Flucloxacillin
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Questions: briefly describe the action of the following classes of anti-infective agents: Beta-lactams it is a drug class that affects bacterial cell wall synthesis. Some antibiotic containing these agents are penicillins, cephaloporins and carbapenems. Glycopeptides it is also a drug class that affects bacterial cell wall synthesis. Vancomycin is one of the ab drug with this agent. Aminoglycosides it is a drug class that affect protein synthesis. It is a board spectrum that binds with smaller ribosomal subunits 30s. Marcrolides it is a drug class that affects protein synthesis. It is a board spectrum that binds with the bigger ribosomal subunits 50s. Some drugs with this agent are azithromycin, clarithromycin and erythromycin: identify the significant risks related to these classes. Beta-lactams anaphylaxis (rare), urticarial, skin rash, itching and angioedema. Glycopeptides red man syndrome or/and renal impairment. Aminoglycosides significant risks with these drug classes are nephrotoxicity, neurotoxicity and ototoxicity.
