BIOL123 Lecture Notes - Lecture 24: Endochondral Ossification, Hyaline Cartilage, Ossification

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17 Jun 2018

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• Endochondral ossification:

o Original model is hyaline cartilage

o All bones (except skull and clavicles) develop by endochondral ossification

o Commences before birth, continues throughout childhood and into early adulthood

o Primary ossification centre: first occurs in the shaft of the bone (diaphysis)

o Secondary ossification centre: occurs in the ends of the bone (epiphysis)

o Bone continues to grow in length by continued ossification at the metaphysis

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