L43 GeSt 123 Chapter Notes - Chapter 2: Neurofibrillary Tangle, Senile Plaques, Cerebral Circulation
22 Nov 2016
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Brain health in aging: a lot of people feel that mental deterioration is inevitable and thus do not feel motivated to work to fix/prevent it, people fear the loss of mental capacity more than they do physical capacity. Cognition and the aging brain: how does the brain normally age? functions. No definition for normal aging of the brain --> difficult to distinguish abnormal cognitive. Brain naturally undergoes structural and functional changes. 10% loss of brain volume after age 80 due to shrinking of brain parenchyma. Senile plaques and neurofibrillary tangles --> may lead to alzheimer"s. Evidence includes amelioration of age-related deterioration and successful cortical remodeling of elderly brain. The brain rearranges itself to compensate for loss of functionality of some regions. Cognition refers to one"s language, memory, reasoning, etc. skills. Cognitive function and behavioral changes with age --> not necessarily due to disease.
