BISC401 Chapter 8-12: Molecular Bio
29 Nov 2016
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Document Summary
Eukaryotic genes, transcription control regions known as enhancers can lie 50 kb or more from the coding region. Poly a sites specify 3" cleavage and polyadenation. Trna, rrna, mirna, and sirna are just rna sequences not proteins. Mrnas are said to be polycistronic; a genetic unit encoding a single polypeptide or monocistronic; each rna molecule encodes a single protein. The cluster of genes that forms a bacterial operon constitutes a single transcription unit which is transcribed from a specific promoter in the sna sequence to a termination site producing a single primary transcript. Approximately 90% of human transcription units are complex. Processed pseudogenes: nonfunctional genomic copies of mrnas. Cloning and sequencing of the beta globin gene clusters from various primate species has provided strong evidence that the human hgb1 and. Hgb2 genes encoding fetal beta globins arose from an unequal homologous crossover between two l1 elements flanking an ancestral globin gene.
