BILD 3 Chapter Notes - Chapter 8: Hox Gene, Evolutionary Developmental Biology
30 May 2016
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1. a. i. 1. organisms to understand how these processes have evolved and how changes in them can modify existing organismal features: widespread conservation of developmental genes among animals. A 180 nucleotide sequence which specifies a 60 amino acid homeodomain in the encoded proteins. Evolved very early in the history of life. Homeotic genes in animals were named hox genes. Short for homeobox-containing genes because homoetic genes were. 1. a. i. the first genes found to have this sequences. Homeoboxes are present not only in the homeotic genes but also in the egg0polarity gene bicoid, in several of the segmentation genes, and in a master regulatory gene for eye development. Homeodomain is the part of a protein that binds to dna when the protein functions as a transcriptional regulator. Proteins with homeodomains probably regulate development by coordinating the transciption of batteries of developmental genes, turning them on or off. These are used in all kinds of animals" development.
