BSC 2010C Chapter Notes - Chapter 16: Erwin Chargaff, X-Ray Crystallography, Frederick Griffith
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Frederick griffith studied pneumonia bacteria: he had two strains, a pathogenic one & a nonpathogenic one, once the pathogenic bacteria were killed & then mixed with the nonpathogenic strain, some of the cells became pathogenic. Transformation: a change in genotype & phenotype due to the assimilation of external. Dna by a cell: when the external dna is from a member of a different species, transformation results in horizontal gene transfer. Virus: an infectious particle incapable of replicating outside of a cell, consisting of an. Rna or dna genome surrounded by a protein coat (capsid) and, for some viruses, a membranous envelope. Proteins contain sulfur so the sulfur only labeled the protein. This experiment was so important because it provided evidence that nucleic acids, not proteins, are hereditary material for certain viruses. Erwin chargaff discovered that the base composition of dna varies from one species to another. Chargaff also discovered the regularity of ratios of nucleotide bases (the number of.
