BIS 101 Chapter Notes - Chapter 4: Karyotype, Intermediate Frequency, Mendelian Inheritance
10 Oct 2016
School
Department
Course
Professor
Document Summary
Textbook chapter 3- mapping eukaryote chromosomes by recombination. Gene position is crucial information needed to build complex genotypes required for experimental purposes or for commercial applications. Knowing the position occupied by a gene provides a way of discovering its structure and function. A gene"s position can be used to define it at the dna level. The genes present and their arrangement on chromosomes are often slightly different in related species. By comparing such differences, geneticists can deduce the evolutionary genetic mechanisms through which these genomes diverged. Chromosome map: a representation of all chromosomes in the genome as lines. Marked with the positions of genes known from their mutant phenotypes, plus molecular markers. Loci: the specific place on a chromosome where a gene is located. Key concept: genetic maps are useful for strain building, for interpreting evolutionary mechanisms, and for discovering a gene"s unknown function. Discovering a gene"s function is facilitated by integrating information on recombination-based and physical maps.
