BIOLOGY 1114H Chapter Notes - Chapter 23: Allele Frequency, Genetic Drift, Gene Pool

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Evolutionary change is only apparent in a population of organisms over time. Genetic variation: differences among individuals in the composition of their genes. Can be quantified at the whole gene level as average percentage of loci that are heterozygous. Not all phenotypic variation results from genes, some are acquired characteristics. A point mutation (change of a single base) can have a significant impact on phenotype. Neutral variation: differences in dna structure caused by point variations that don"t cause significant selective advantage or disadvantage. Chromosomal changes that disrupt loci are usually harmful. Usually occur due to errors in meiosis, slippage in dna replication, or activities of transposable elements. Duplication of chromosomes is almost always harmful but duplication of smaller segments can be beneficial and take on new functions. Prokaryotes produce more genes and thus more mutations per unit of time. Genetic material is unique combination of alleles received from parents.

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