BIOL 2051 Chapter : Viral Replication Unit 5 Biol2051
Document Summary
Viral replication: attachment (adsorption) to specific receptor on host cell, usually a membrane protein. ** viruses are host specific may act on related species but do not cross. -eukaryotic: whole virus/virion by endocytosis: penetration (injection, some are uncoated at cytoplasmic membrane to release virion contents into cytoplasm, some uncoated in cytoplasm, some uncoated in nuclear membrane and contents into nucleus; ***all virion genomes makes their way to nucleus for replication! -simple virions: lyse/kill host cell: uncoated; protein coat remains outside and viral dna enter, synthesis of nucleic acid and protein host machinery replicates viral genomes into capsids to make new virions maturation . -enveloped virus: by budding enveloping itself with host cell membrane that it decorated with its own proteins; nucleocapsid with protein coat . Abcdefg by dna polymerase (gets all it needs plus 2 extra; t4"s aren"t identically replicated) infection phage dna replication (early mrna for early proteins,