BIOL 2051 Chapter : Chapter 8
Document Summary
Each virus has a specific range/type of cell that it can infect. The range is dictated by interaction between viral attachment proteins and host cell receptor molecules: host cell receptors are often molecules critical for cellular functions (and therefore not easily eliminated to prevent infections), receptor/virus pairings: Lambda (bacteriophage that infects e. coli: ways different viruses can attach to cells: Viral entry and uncoating: entry of enveloped viruses (i. e. influenza) Endocytosis then fusion of viral envelope with host plasma membrane. Binding of the virus is followed by endocytosis. Acidification of the resulting endosome causes a conformational change in the hemagglutinin protein, exposing a fusion peptide. The viral envelope then fuses with the endosomal membrane, releasing the virus rna into the cytoplasm. 5: group vi, retroviruses (+) strand rna which is transcribed into double-stranded dna by enzyme reverse transcriptase (single-stranded rna to single-stranded dna to double-stranded dna, must package reverse transcriptase with genome dsdna is then integrated into host genome.
