BIOL 1201 Chapter : BIOL 1201 3 27
Document Summary
Synthesis of proteins directed by genetic information: dna directs the synthesis of proteins. The central dogma: dna is transcribed into mrna, mrna is translated into protein, exceptions, reverse transcriptase (h. temin and d. baltimore, telomerase (elizabeth h. blackburn, carol w. greider and. Ribonucleic acid (rna: ribosomal rna (rrna, transfer rna (trna, messenger rna (mrna) Rna synthesis: rna polymerase, formed on the template strand of dna, the rna is anti-parallel to the dna, rna polymer grows in the 5" to 3" direction, monomer added to the 3" oh of the polymer. Rna processing: in the nucleus of eukaryotes, rna processing not seen in prokaryotes, addition of a 5" gtp cap, addition of a poly-a tail, removal of introns (intervening sequences) Rna processing in eukaryotes: intron (intervening sequence) is the non-coding sequence and is removed from the mature mrna, exon (expressed sequence) codes for a sequence of amino acids. Protein domains: modular architecture, functional units of the protein.
