BIOL 118 Chapter Notes - Chapter 21: Myod, Stem-Cell Therapy, Femur
26 Apr 2017
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Can be inside or outside the cell. Response: gene expression changes and cells may divide, differentiate more or die. Ex: webs in fingers and toes cells during development will go through apoptosis. Ex: abort halt of neurons die during the nervous system wiring. Some cell death signals found in worms, flies, and other mammals. Inappropriate activation of programmed cell death contributes to als, pd, ad etc. A failure to undergo apoptosis contributes to cancers. Regulatory transcription factors are most important in development. Morphogens drive pattern formation and are present in concentration gradients. 21. 6 - discovery of the bicoid morphogen. Back in the day scientists bombarded fruit flies with mutations. One called a bicoid affects anterior posterior axis. Bicoid mrna distributed in gradient in fly embryos. Bicoid mrna is made by cells of mother and transferred into egg. Gap genes turned on and give rise to different morphogens.
