PHIL 2130 Chapter Notes - Chapter 3.1: Endoplasmic Reticulum, Neurovascular Bundle, Muscle Fascicle

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Surrounded by perimysium, filling spaces between fascicles. Contain filamentous proteins called myofibrils within its sarcoplasm. Tethered to skeletal muscle fibres via ct to allow contraction. Collagen fibres epimysium, permysium, and endomysium all blended together, attach to bone. Attach to bone via collagen interwoven with periosteum. Cemented to bone of matrix known as sharpey"s fibres. Blood and nerve supply form neurovascular bundle, branch within ct to reach individual muscle fibres. Skeletal muscle fibres are large multinucleated cells, formed from myoblast cells. Sarcolemma: cell membrane of skeletal muscle fibre, wraps arou. T/transverse tubules: tubular extensions of sarcolemma perpendicular of to cell surface. Triad: 2 t-tubule with adjacent terminal cisternae. Terminal cisternae is expansions of sarcoplasmic reticulum of t-tubules. Sarcoplasmic reticulum is endoplasmic reticulum of muscle fibre. Myofibrils: bundles of myofilaments, length of muscle fibre. Myofilaments: filamentous polymers, has actin (thin filaments), and myosin (thick filaments) Strength: microtubules > intermediate filament > actin filament. Sarcomeres: contractile unit of striated muscle, striation.

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