NATS 1575 Chapter Notes - Chapter 9: Microsatellite, Str Analysis, Restriction Fragment Length Polymorphism
3 Mar 2017
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Document Summary
The latest method of dna typing, short tandem repeats (str) analysis has emerged as the most successful and widely used dna profiling procedure. Short tandem repeats: a region of a dna molecule that contains short segments of three to seven repeating base pairs. Strs are locations (loci) on the chromosome that contains short sequence elements that repeat themselves within the dna molecule. They serve as helpful markers for identification because they are found in great abundance throughout the human genome. Strs normally consist of repeating sequences of three to seven bases; the entire strand of an str is also very short, less than 450 bases long. These strands are significantly shorter than those encountered in the rflp procedure. Strs are much less susceptible to degradation and are often recovered from bodies or stains that have been subject to extreme decomposition.
