NATS 1540 Chapter Notes - Chapter 3.2: Heparin-Induced Thrombocytopenia, Rivaroxaban, Fondaparinux

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Venous thromboembolism case learning objectives (suggested resources included in brackets) Briefly describe the role of each antithrombotic listed below in the management of vte (including a short description of efficacy). Develop a drug chart to compare and contrast the relevant pharmacokinetics, dosing, clinically important drug interactions, and monitoring parameters (including lab test): unfractionated heparin, summarize the clinical presentation of heparin induced thrombocytopenia. (accp guideline chapter, dipiro). Iv infusion vs. sc administration) fondaparinux: low molecular weight heparins, rivaroxaban, warfarin. Evaluate the efficacy of rivaroxaban for the treatment of vte ( einstein. Duration of therapy describe recommended duration of anticoagulation therapy in patients with venous thromboembolism. (accp guidelines) Warfarin initiation dosing: develop a response to case 1 on warfarin initiation therapy. Summarize a general approach for initiation dosing of warfarin. (accp guidelines) Warfarin maintenance dose: develop a response to case 2 & 3 on warfarin maintenance therapy. Supratherapeutic inrs - summarize the accp guidelines on the management of supratherapeutic.

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