BIOL 2021 Chapter Notes - Chapter 20.2: Inner Cell Mass, Embryonic Stem Cell, Blastocyst

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Must destroy the cancerous bone marrow with targeted radiation or chemotherapy. Harvest bone marrow from a tissue-matched donor or healthy cells from the patient"s own bone marrow before therapy. These cells are injected into the patient. Needs to be a match in order to reduce immune rejection. Culture cells from patches of undamaged skin. Epidermal stem cells from that patch will divide, and become cultured skin. This can be transplanted to the patient. Outer cells of the blastocyst are called extraembryonic (placenta) Inner cell mass produces the actual embryo. The inner cell mass can be removed and grown in culture embryonic stem cells (es cells) These cells are pluripotent: can become any adult cell but can not create placenta. Es cells can divide indefinitely in culture. Es cells in culture can be induced to differentiate into different cells with different signals.

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