PS268 Chapter Notes - Chapter 13: Elizabeth Barrett Browning, Thomas De Quincey, Samuel Taylor Coleridge
Document Summary
Writers and opium: the keys to paradise: wrote about the joys of opium, elizabeth barrett browning, samuel taylor coleridge, thomas de quincey withdrawal pains. India: where opium smuggled from, poppy plants abundant made opium illegal) Morphine: friedrich sert rner: isolated primary active ingredient opium (10x stronger, morphium/morphine: active ingredient in opium, codeine: 2nd most important alkaloid derived from opium, morphine use increased due to: Invention of syringe: pain relief for soldiers in war. Heroin: morphine + 2 acetyl groups = heroin, 3x stronger than morphine (enters brain more rapidly & more potent, same effects as morphine, originally non-addictive cough-suppressant to replace morphine & codeine. Rise in medical use of prescription opioids for pain relief but also other: canada"s rankings, #1 for dilaudid, #2 for morphine & oxycodone, #3 for vicodin, 1% adults used heroin, 0. 29% used in past year. Naloxone: reverse the depressed respiration resulting from opioid od. If given to someone physically dependent, can cause immediate withdrawal symptoms.
