BI110 Chapter Notes - Chapter 9: Eukaryotic Translation, Transfer Rna, Release Factor
Document Summary
Initiation factors recruit the small ribosomal subunit and trnamet to the 5 cap and scan the mrna for an aug codon. When the complex reaches an aug the large ribosomal subunit joins the initiation factors are released and a trna complementary to the next codon binds to the a site. A reaction transfers the met to the amino acid on the trna in the a site, forming a peptide bond. The ribosome moves down one codon which puts the amino acid carrying the polypeptide into the p site and now the uncharged trna into the e site, where it is ejected. A reaction transfer the met to the amino acid on the trna in the a site, forming a peptide bond. The ribosome moves down one codon, which put the amino acid carrying the polypeptide into the p site and the now-unchanged trna into the e site, where it is ejected.