BI110 Chapter Notes - Chapter 26: Citric Acid Cycle, Nadh Dehydrogenase, Electron Transport Chain

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3 Feb 2017
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Module 26 - cellular respiration ii: the citric acid cycle and oxidative phosphorylation. Pyruvate + coa + nad+ acetyl-coa + nadh +h + Pyruvate must be transported across 2 membranes. Non selective porin allows diffusion across omm. Pyruvate oxidation is a 3 step process catalyzed by a large complex called pyruvate dehydrogenase. 8 steps in the cycle, each with its own enzyme to catalyze the reaction. Succinate dehydrogenase is on the inner mitochondrial membrane. For every acetyl-coa molecule, 2 co 2 , 3 nadh, 1 fadh 2 and 1 gtp are released. One turn of citric acid cycle: 1-acetyl-coa + 3nad + + 1fad + 1adp + 1pi + 2h 2 o . 2co2 + 3nadh + 1fadh 2 + 1 atp + 3h + + 1coa. Electrons passed from nadh and fadh 2 to o 2. 4 membrane protein complexes (inner mitochondrial membrane) 2 smaller mobile electron carriers - ubiquinone (uq) and cytochrome c.

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