Biology 1202B Chapter Notes - Chapter 12: Enterobacteria Phage T2, Phosphodiester Bond, Escherichia Coli

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Dna can be subject to breakages o o. Believed that amino acids (proteins) were the origin of informaion. Griith found that 1 of 2 strains (which has a polysaccharide capsule around the cell) is the diference between having pneumonia or not (from bacterium). o. Even when living r cells (non-virulent) was injected with dead s cells (virulent), the r cells managed to acquire the capsule, also making the r strain virulent. Avery"s experiment of determining the reason behind the deadliness of the capsule o. Ater destroying all dna, did the transformaion not occur. Didn"t make sense to most scienists that 4 nitrogenous bases had more informaion than 20 amino acids. Hershey and chase studied the efect of e. coli (bacteria) from bacteriophage t2 (virus). o o o. T2 phage is only core of dna surrounded by proteins. Protein was tagged with sulfur (35), while dna was tagged phosphorus (32)

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