Biology 1202B Chapter Notes - Chapter 16: Open Reading Frame, Genome Project, Dna Sequencing

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Genomics is the characterization of whole genomes, including their structures (sequences), functions and evolution. Modern dna sequencing techniques are advances on methods originally used to analyze the sequences of cloned dna sequences and dna sequences ampli ed by polymerase chain reaction (pcr) As part of the of cial hgp, the genomes of several important model organisms commonly used in genetic studies were sequenced for comparison: e. coli (representing prokaryotic cells), the yeast. Drosophilia melanogaster and caenorhabditis elegans (the fruit y and a nematode work, representing multicellular invertebrate animals), and. A vast amount dna sequence data has been generated by genome sequencing projects: for those sequences to be useful, they need to be available centrally for access by all researchers. Many other genomics databases are accessible using the internet, with sequence data organized in different ways. Genomics consists of 3 main areas of study: genome sequence determination and annotation, determining the functions of genes, study how genomes have evolved.

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