NFS382H1 Chapter Notes - Chapter 2: Zinc Sulfate

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The aim of this study was to determine effects of supplemental zinc on physical growth in preschool children with retarded linear growth. Ninety children were randomly assigned in zinc group (zg) or placebo group (pg). After 6 months of zinc or placebo supplementation, we followed up the children for another 6 months. Anthropometric indicators were measured before the intervention and then monthly for 11 months. The most significant (p=0. 001) effect of zinc supplementation was seen in boys" height increment at the end of follow-up period. Several studies indicate that zinc deficiency results in poor growth in infants [4, 5] and children, and also decreased appetite. It is now well established that malnourished children, including those with diarrheal diseases, are in negative zinc balance and would, therefore, benefit from zinc supplementation. Our hypothesis was supplementing zinc to preschool children with retarded linear growth would have positive effects. The study was designed as a community-based randomized, double-blind, placebo- controlled supplementation trial.

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