KIN217 Chapter Notes - Chapter 4: Ribonuclease, Fibril, Random Coil
Document Summary
Proteins are the embodiment f the transition from the 1d world of dna to the 3d world of molecules capable of diverse activities. Dna encodes the aa sequence that make up a protein primary structure. Functioning proteins are long aa polymers that fold to form discrete 3d structures w/ specific biochemical functions. Secondary structure 3d structure that results from a regular patter of h-bonds b/w the nh and co components of aas. Tertiary structure 3d structure becomes more complex when the r groups far apart in the primary structure bond w/ one another. Highest level of structure an individual polypeptide can attain. Many proteins require more than one chain to function. Quaternary structure varies in complexity; can be 2 identical polypeptide chains or dozens of different polypeptide chains. The final 3d structure of a protein is determined simply by the aa sequence of the protein. 4. 1 primary structure: aas are linked by peptide bonds to form polypeptide chains.