KNES 437 Chapter Notes - Chapter 4: Dopaminergic Pathways, Peptide Yy, Addiction

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Stimulates dopaminergic pathways: leptin relays information to the brain about the body"s fat reserves it decreases food intake and increases metabolic rate. Insulin and peptide yy relay information to the brain about changes in energy levels. In rats, it was found that elevated blood triglycerides after a high fat meal was a predictor for increased caloric intake. Stress also predisposes drug addicts to relapse, and is a significant cause of failure in dieters. It has been hypothesized that humans can become addicted to refined foods (the refined food hypothesis"), which contain processed sugars, fat, salt, flour, caffeine, or all, but not to unrefined foods. Genetic and environmental influence: the genetic and environmental influences on the risk of becoming overweight or obese are substantial and could not be adequately treated within the scope of this review. Intrauterine environment may significantly impact a child"s subsequent risk of developing certain health issues: exercise may decrease the effects of genetic influence in adolescents.

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