CHY 183 Chapter Notes - Chapter 9: Southern Blot, Restriction Fragment Length Polymorphism, Product Rule

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22 Jan 2017
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* discovery of deoxyribonucleic acid (dna), the deciphering of its structure and the decoding of it"s genetic information were turning points in understanding inheritance. * alec jeffreys were responsible for the discovery that genes were individual to each person. * genes are the fundamental unit of heredity composed of dna and are arranged along chromosomes. * first breakthrough was by watson and crick who deduced the structure of dna. * dna molecule is composed of 2 dna strands coiled into a double helix formation where bases were aligned on each side; a to t, g to c (complementary base pairing) * inheritable traits controlled by dna arise out of it"s ability to produce proteins which are made by linking amino acids; the shape and function of the protein is determined by the sequence of amino acids. * single changes in base/letter can result in illness or deformities. * replication: synthesis of new dna from existing dna.

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