BIOL 102 Chapter Notes - Chapter 6: Lipid Bilayer, Uniporter, Membrane Transport
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Lipids/proteins can move laterally to each other within membrane. Leaflet: half of a phospholipid bilayer: each face different region, ex. : cell membrane cytosolic leaflet (faces cytoplasm) and extracellular leaflet (face cell exterior) o. Difference between leaflets occurs with glycolipids (lipids attached to o carbohydrates) Cells can change phospholipid composition of leaflet: move phospholipid from one leaflet to other. 3 proteins that can transfer: scramblases: transfer phospholipids along concentration gradient. No atp needed: flippases: move lipids from outer leaflet to inner, floppases: inner leaflet lower leaflet. Both require energy from hydrolysis: describe the fluidity of membranes, how it is affected by lipid composition, and how it affects an organism"s ability to adapt to its environment. Peripheral membrane proteins: non covalently bound to integral membrane proteins or polar head groups of phospholipids, hydrogen/ionic bonds, causes conformational change that allows communication, if shape changes protein leaves, conformational change depends on hydrogen bond flexibility.
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