HTHSCI 3C04 Chapter Notes - Chapter 15: Relative Risk, Odds Ratio, Sensitivity Analysis
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Evaluation of studies of treatment or prevention interventions: are the results of the study valid, was the assignment of patients to treatments randomized? i. Allocation concealment: was follow-up sufficiently long and complete? i. Co-intervention: treatment is undermined by extra care given to one group and not the other important that this does not occur: were the groups similar at the start of the trial? i. The effects of individual treatments are measured using on or more outcome measures (dichotomous or continuous) Absolute risk difference (ard) tells us how much of the effect is a result of the intervention itself. The true effect of a treatment is never really known instead we use the results of trials, which are estimates of effect; each estimate is a neighbour of the true treatment effect. Are my patients so different from those in the study that the results don"t apply? i.