PSYC 211 Chapter Notes - Chapter 4.5: Potassium Channel, Benzodiazepine, Cerebral Cortex
3 Jun 2016
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Document Summary
Norepinephrine (ne or noradrenalin), like ach, is found in neurons in the autonomic nervous system. Excess ne is destroyed by mao-a (inhibited by moclobemide). Almost every region in the brain receives input from noradrenergic neurons. Most neurons that release ne do not do so through terminal buttons on the ends of axonal branches, but instead through axonal varicosities. There are several types of noradrenergic receptors, identified by their differing sensitivities to various drugs; they are actually called adrenergic receptors because they are sensitive to epinephrine as well. Four types of receptors are fond in various organs of the body and are responsible for the effect of epinephrine and ne when they act as hormones outside the cns. Adrenergic receptors produce both excitatory and inhibitory effects: generally, the behavioural effects of the release of ne are excitatory. Serotonin (5-ht) plays a role in the regulation of mood; in the control of eating, sleep, and arousal; and in the regulation of pain.
