Exploring the potential impacts of individual factors on ADME

Scenario:

Joanne is a 35-year-old female with a medical history of stomach complaints but no evidence of ulcer. When Joanne visited the clinic this morning, she weighed in at 324 pounds. ¡ She presented with upper respiratory symptoms attributable to allergy and was prescribed a decongestant and an antihistamine.

 

1. Read the scenario a couple of times, making sure to pay attention to the details.
2. Write down factors about the individual that you can identify from the scenario.
   § Think about the factors discussed on slides 4 and 5
3. Look at the factors that you listed in Step 2 and write out the ones that you
   believe should be considered when determining the drug dose that should be
   given.
   § Are there any factors that you believe would require the drug dose to be
   increased or decreased?
4. For each factor you identified in Step 3, write down what part of ADME they could
   affect.
   § In some instances, it could be more than one.
   § You can also consider administration here.
5. Pick one of the factors you identified in Step 4 and one of the parts of ADME (if
   there is more than one) and explain in detail how that factor affects that part of
   ADME.
6. Make a recommendation, based on the explanation that you provided in Step 5,
   for how the drug dose or other feature should be changed.
7. Repeat steps 5 and 6 for each of the other factors you identified, each time
   focusing on a different part of ADME (or another feature).

Identify which challenge you will participate in and which city you will design or redesign. You research the climate and geography of the city's location to identify how the city design is influenced by climate and natural disasters.

Sim City

CP1:Identifying Environmental Issues

[Student Name]        [Class Block/Period]

Student Work: Challenge Choice and City Description

Student Work: Main Environmental Issues

Student Work: MLA Citations

Self-Assessment

Level

Rationale - Write a short paragraph justifying the numerical level score you chose using key terms from the rubric and examples from your work.

Checkpoint Directions

As you design or redesign your city, there are many possible environmental issues that you must address in your plan. All cities must deal with pollution issues, therefore all plans for this project must address water pollution, air pollution, and solid waste.  After you have addressed those issues, you must also identify additional critical environmental issues your specific city faces.  These could be due to population size, climate, landscape, ecology, past development, climate change, development or any other environmental, social, or economic factor.  In this checkpoint you will research and identify the environmental issues. In the next checkpoint you will research and identify solutions to each issue.

Check for Resources and Activities under this checkpoint that will help you complete this checkpoint.

Read the “City and Challenge Choices” resource that accompanies this checkpoint. Refer to it for more detailed directions for this checkpoint and what to write in the student work sections.

Choose a challenge and describe your choice in the appropriate box above.

Choose a city based on your challenge choice and describe it in terms of climate, geography, geology, population, and ecology.  Choose details that will affect development, agriculture, and industry.  Cite sources for information about your city.

Identify environmental issues that your city will have to address. There should be a wide variety of issues including, but not limited to, pollution, water use, climate change, resource use, land use

For each environmental issue, cite information from at least one source.

Create a works cited list in MLA format in the space provided above for all the sources you cite. You can use Easybib.com as a guide.

Checkpoint Checklist