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19 Jan 2022

Background and context

Ubiquitin modification has emerged as an important mechanism that regulates cell signalling through proteasome-independent mechanisms. It is best known for its role in targeting protein degradation by the proteasome. The NF-B pathways, which regulate a variety of physiological and pathological processes in response to various stimuli, are a good example of ubiquitin's versatility as a signalling tag.

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