ANAT1053 Lecture Notes - Mucous Membrane, White Blood Cell, Neutrophil

• School: George Brown College
• Department: ANAT
• Course: ANAT1053
• Professor: Rickson Valtellini

Document Summary

First line of defense: skin and mucous membranes. Second line of defense: several innate defense mechanisms: leukocytes and macrophages, antimicrobial proteins, natural killer cells, inflammation, Third line of defense: adaptive immunity: defeats a pathogen, and leaves the body with a memory of it so it can defeat it faster in, innate defenses guard equally against a broad range of pathogens. Three kinds of innate defenses: protectiveproteins: protectivecells, protectiveprocesses. Local (except for fever), nonspecific, lacks memory: adaptiveimmunity bodydevelopsseparateimmunityto each pathogen, has a memory of. Body adapts to a pathogen and wards it off more easily upon future exposure (memory) Innate body defences -cells and chemicals: protective cells (, e. g. , leukocytes, macrophages) Phagocytes (e. g. , leukocytes like natural killer cells) inflammatory response. Fever: aggressive lymphocytes, release chemicals called perforins to target the foreign cell"s membrane and form, can lyse (disintegrate or dissolve) and kill cancer cells, virus-infected cells; Innate body defences - natural killer (nk) cells pores, leading to cell death.