Biology 3316A/B Lecture Notes - Lecture 15: Heat Shock Protein, Cxcr4, Diapause
Document Summary
Lecture 15 egf and notch signalling + juxtacrine. Dauers do not undergo this shift toward aerobic respiration. Relative to growing larvae, dauers also appear to be transcriptionally quiescent but have elevated levels of mrna encoding the heat shock protein hsp90. Dauers are adapted to resist metabolic stress and is consistent with the observation that they are long-lived. If there is limited food, dense population and high temperatures -> L2d stage and in 13 hours -> dauer. Stage -> once there is plentiful good, sparse population and temperate environment -> l4 stage: diapause: a period of suspended development in an insect, other invertebrate, or mammal embryo, especially during unfavorable environmental conditions. Introduction of an equivalence group: basement membrane that have vital vulval precursor cells and an anchor cell gets attached to it and it drags along and begins to pull upward. Anchor cell establishes lumen in vulf and later withdraws via fusin with the utse cell.
