Global Health and Health Policy 50 Lecture 1: Blood Transfusions
Document Summary
Packed rbc, platelets, fresh frozen plasma, albumin, clotting factors. Universal bar-coding system requirements: unique facility identifier, lot number relating to the donor, product code, abo group & rh type of donor. Bacterial transfusion reactions: caused by infusion of contaminated blood products, symptoms, tachycardia, hypotension, fever, shock, onset is rapid. Allergic transfusion reactions: also called anaphylactic transfusion reactions, more common in people with hx of allergy, manifestations, urticaria. Itching: bronchospasm, anaphylaxis, onset: during-24 hrs after, reduce risk, leukocyte reduced, washed rbc. Circulatory overload: caused by blood product infusing too quickly, more common when whole-blood transfusions or when the patient receives multiple transfusion, older adults are most at risk, manifestations, hypertension, bounding pulse, jvd, dyspnea, restlessness, confusion, prevention, monitoring i&o. Transfusion-associated graft-versus host disease (ta-gvhd: occurs in immunosuppressed and immunocompetent patients, caused by donor t-cell lymphocytes attack host tissue, onset within 1-2 weeks, manifestations, thrombocytopenia, anorexia, anemia, nv, chronic hepatitis, weight loss, recurrent infection.