PSY 320 Lecture Notes - Lecture 2: Autopsy, Microinjection, Cannabinoid Receptor Type 1
Document Summary
Experiment: a study with learning and navigating a water maze shows that learning has a curve, could use an agonist and an antagonist, antagonist- makes it so neurotransmitter does not have an effect. Ex: sit on receptor to avoid receiving of neurotransmitters: systemic injection- in general inject to reach the brain- ex: using a syringe injection into stomach and gets into the blood stream. Inducible genetically different animals have gene but on either side of the dna there are markers that allow you to control whether gene can be expressed or not. For entire life the gene can be in on position. But when you want to examine it without active gene, you can change the gene in the animal (ex: a diet change. ) Ex: inject into the hippocampus to decrease ability to produce cb1 receptor: say you want to hyper express the receptors- have the gene be inserted into that part of the brain.
