MICROBIO 140P Lecture Notes - Lecture 3: Francesco Redi, Louis Pasteur, Smallpox
Document Summary
First important contribution: fermentation yeast act as catalyst and mediator through a serious of reactions that convert sugar into alcohol. Greeks (including aristotle) believed in abiogenesis life came from inanimate objects. Hundreds of years earlier francesco redi meat and fly experiment. Removing infected worms saved the rest: robert koch (germany) Anthrax (bacillus anthracis) intestinal, inhalation or cutaneous (through breaks in the skin) infection. Observed that it had to do with livestock based on who got sick with it. Bacterial culture growing bacteria in artificial media. Soft or hard media (liquid or solid) containing nutrients for growth of bacteria. The same microorganisms are present in every case of the disease. The microorganisms are isolated from the tissues of a dead animal and a pure culture is prepared. Microorganisms from the pure culture are inoculated into a healthy susceptible animal, the disease is reproduced. The identical microorganisms are isolated and re- cultivated rom the tissue specimens of the experimental animal.