BIOLOGY 305 Lecture Notes - Lecture 5: Ascus, Centromere, The Sequence

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21 Jul 2016
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We are going to use recombination frequency as a way to order genes on a chromosome. The sequence of the dna has to match for recombination to occur. The longer the homologous dna, the higher the chance of recombination. We see three genes, a b and c and a b and c, on two homologues chromosomes and crossover happened. Crossovers can happen between multiple chromatids at the same time. The longer the distance between two genes, the more different places that crossing over can happen. If there are an odd number of crossovers, you"ll get the recombinant phenotype. If there are an even number of crossovers, you"ll get the parental phenotype. The point of all of this: the further things are, the likely recombination will happen. If you see a lot of recombination, it must be true that the two things are far apart.

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