BIOLOGY 207 Lecture Notes - Lecture 27: Aliivibrio Fischeri, Biofilm, Signal Transduction
Document Summary
Methyl-accepting chemotaxis proteins (mcps) clustered at cell poles bind. The cytoplasmic domains of each mcp binds to the chea kinase and controls its. Initiates a series of events lowering chey-p levels. Reversible methylation or demethylation of mcps desensitizes or sensitizes mcps, chemoattractants. activity. respectively. The cell not only knows it is moving towards a chemoattractant. The system also knows if it is moving up the chemoattractant gradient! The bacterial cell is not just recognizing and chemoattractant, it can recognize where it is in the gradient. And the way that the cells able to do this is by methylating or demethylating these methyl accepting chemotaxis proteins. Methylation desensitizes the mcp from the chemoattractant towards demethylation sensitizing the mcp respectively. Methyl-accepting chemotaxis proteins (mcps)- membrane spanning protein, where the top can recognize a chemoattractant and the bottom is in the cytoplasm. Chew connects the mcp to chea ( chea is the kinase that can phosphorylate chey) if no attractant.
