BIOLOGY 207 Lecture Notes - Lecture 19: Groes, Protein Folding, Microorganism
Document Summary
Protein folding some proteins can fold spontaneously on their own, but many require the help of proteins called chaperons: chaperones : proteins that help fold other proteins. Clamps down on a polypeptide to assist folding. Protein to be folded fits inside a stacked ring with a hollow center. Much more complex than dnak of like a barrel the chaperone protein can fit inside of this barrel. Groel forms a stacked ring with a hollow center, sort. Groes comes along, as the caps to control the entrance and exit from this chamber. It"s basically cycles of atp binding and hydrolysis that causes confirmation of changes within the chamber that helps fold the protein. requires atp binding and hydrolysis. Protein degradation: cleaning house the presence of useless or degraded proteins can hurt the cell and must be destroyed: many normal proteins contain degradation signals called degrons . degrons can dictate stability of of protein.
