CBIO 3400 Lecture 8: CBIO 3400 2:20
20 Feb 2019
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Document Summary
Mitochondria are dynamic organelles, they are continually fusing and breaking. Motors are moving mitochondria around such as kinesins and dyeins. Oxygenation catastrophe: great oxygenation event- release oxygen and rust out the early earth, when oxygen 1st developed on earth, it wiped out nearly 90% of earth, endosymbiosis- mitochondria formed because of an endosymbiotic event. To survive, this toxic environment cells needed a way to detoxify itself. They acquired aerobic prokaryotes to serve this function: some modern protists acquire photosynthetic endosymbionts (temperately) Inner membrane: respiratory chain and atp synthase. Impermeable to most charged molecules: outer membrane, permeable to larger molecules, matrix. Mitochondria what he wants us to know (mechanism: makes atp, chemiosmotic theory with using a proton gradient to produce atp, chemiosmotic coupling: Overview of oxidation phosphorylation: cac produces co2, nadh, as electrons flow down the respiratory chain, they induce the pumping of protons. Conformation change drives channel opening to pump protons out: electrons are falling down this pathway.
