BCMB 3100 Lecture Notes - Lecture 1: The Double Helix, Semiconservative Replication, Pentose

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Lecture 11/17 notes: has 2 components: pentose sugar (ribose or deoxyribose) and nitrogenous base (purine or pyrimidine, no phosphate group. Nucleotide: has 3 components: pentose sugar (ribose or deoxyribose), nitrogenous base (purine or pyrimidine), and a phosphate group (you can have 1, 2, or 3 groups, a sequence of 3 base pairs. Dna can only synthesize dna from 5" to 3". Dna is a nucleic acid made of 4 different deoxyribonucleotides. Dna contains the genome and exists as a double stranded helix. Dna is more chemically stable than rna because dna consists of deoxyribose in which there is no hydroxyl group attached to the pentose ring in the 2" position and rna contains ribose. The hydroxyl groups in rna make rna less stable because rna is more apt to hydrolysis. Rna is a long unbranched polymer that has ribonucleotides linked by 3" 5". Rna is very similar to dna except rna contains a u instead of a t.

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