HUN 4446 Lecture Notes - Lecture 7: Peptic Ulcer, Rheumatoid Arthritis, Robin Warren

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Diseases and disorders of the upper gi tract: part 4. Inhibit prostaglandin synthesis and thus mucous production: copd, rheumatoid arthritis require these medications chronically, reduced blood flow, excessive alcohol, smoking, nicotine causes vasoconstriction, trauma, burns. Increase acid and pepsin secretion: diet, black and red pepper, alcohol, caffeine, decaf coffee. Ingestion of food/antacids relieves pain for some or worsens for others: weight gain or loss, nausea/vomiting, emergency symptoms, coffee ground color/appearance hematemesis, melena, diagnosis, typical tests, barium swallow w/ x rays, barium collects in ulcer pit, esophagogastroduodenoscopy. Indications for surgery: gastric retention, severe, uncontrolled hemorrhage, perforation, obstruction, ze syndrome (rare today, many types of surgeries, type of surgery influences nutrition-related complications, gastric surgery. Include protein with meals/snacks: carry foods to treat hypoglycemia, other possible complications of gastric surgery, change in bowel habits, especially with vagotomy, diarrhea or constipation, weight loss. Inadequate intake: malabsorption, anemia, microcytic or macrocytic.

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