BIPN 100 Lecture Notes - Lecture 22: Heart Valve, Heart Sounds, Stroke Volume
13 Jun 2018
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BIPN 100 Lecture 22
5/25/2018
• First heart sound is S1
o Vibrations following closure of the AV valves
o lub
o happens at the beginning of systole
• Second heart sound is S2
o Vibrations generated by closing of the semilunar valves
o dub
• Auscultation is listening to the heart through the chest wall using a stethoscope
• Talk most about the left ventricle because it pumps blood to the whole system of the
body
•
• Stroke volume=EDV-ESV (in mLs)
o 70 mL in a healthy human
• Two periods of isometric in the cardiac cycle: Isovolumic contraction and Isovolumic
relaxation
• Preload: end diastolic volume
o In skeletal, it is the load put on the muscle before contraction
• Afterload: minimum pressure in the aorta (PAO) or diastolic blood pressure
o Muscle generates tension until it overcomes the load and it starts to shorten
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