BIPN 100 Lecture Notes - Lecture 18: Sarcomere, Serca, Troponin

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There is overlap of actin and myosin but there"s no where for the myosin to pull the actin to. The area for any movement is extremely small and therefore the tension and force is also very small. The amount of tension produced when muscle is stimulated is very small. Myosin cannot bind to actin b/c the myosin is too far from the actin to bind to each other. This is because the myosin is far from the actin and there is no overlap between the two and no tension is generated. When we talk about tension and force we are talking about # of cross bridges and shortening of the sarcomere. If not a lot then very little tension, if we have lots of room then we get a lot of tension. The stimulus is long gone by the time the contraction begins.

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