MCDB 21 Lecture Notes - Lecture 6: Bone Marrow, Gastritis, Erythema
22 Apr 2019
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Document Summary
A way to recruit white blood cells to a specific area to fight off an infection/foreign substances. Complex biological response of vascular tissues to harmful stimuli: Accumulation of white blood cells at site of infection/injury. Examples of inflammatory response: chemicals/proteins that promote inflammation -- histamines, cytokines, prostaglandins. Steps in inflammatory response: damaged tissues/bacteria release histamine which increases blood flow, histamine causes capillaries to leak, releasing phagocytic cells & clotting factors causes vasodilation, phagocytic cells engulf bacteria, promoting healing. Flows from arteries arterioles blood capillaries (smallest & highest pressure) Capillaries are porous liquid part of blood moves into tissues. Bone marrow where b cells mature. Lymph fluid moves through lymphatic vessels. Does not contain red blood cells; red blood cells don"t ever leave the bloodstream. Lymphocytes: t cells, b cells, natural killer cells (innate system) Granulocytes: monocytes (turn into macrophages/dendritic cells), mast cells (trigger inflammation), neutrophils (most abundant type of white blood cells) Cytokines soluble proteins that promote immune responses.
