EEMB 40 Lecture Notes - Lecture 21: Plasmodium Ovale, Plasmodium, Salivary Gland
15 Nov 2016
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Document Summary
Nearly 2 million people die every year. In some countries, malaria accounts for 40% of health expenditures. Today, about 1 million people die a year. Primarily kills children but can cause high mortality in adults. Prokaryote: an organism lacking a true nucleus, such as bacteria. Eukaryote: an organism whose cell contain a true nucleus. Closely related to the malaria parasite - hard to kill it without killing ourselves, very little to target. Complex life cycle: a parasite that requires multiple different host species to complete its life cycle. Part of it occurs in mosquito, part of it occurs in humans. Definitive host: the host in which sexual reproduction of a parasite occurs. Mosquito: gametocytes sporozoites (found in mosquitoes salivary glands - injected with coagulants). Sporozoites reach liver within 30 minutes of bite. Infect rbcs, they burst and release the parasites, merozoites, asexual reproduction. When they all rupture - release parasites and cause fever - happen every couple weeks.
