NURS 3664 Lecture Notes - Lecture 28: Capillary Refill, Anaphylaxis, Septic Shock

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Syndrome characterized by decreased tissue perfusion and impaired cellular metabolism. Overall goal: restore blood flow to myocardium by restoring balance between o2supply and demand. Absolute hypovolemia: loss of intravascular fluid volume. Results when fluid volume moves out of the vascular space into extravascular space (e. g. , intracavitary space) Response to acute volume loss depends on: If loss is >30%, blood volume is replaced. Management focuses on stopping loss of fluid and restoring the circulating volume. Fluid resuscitation is calculated using a 3:1 rule (3 ml of isotonic crystalloid for every 1 ml of estimated blood loss) Can occur in response to spinal cord injury or spinal anesthesia (within 30 mins) Loses function of sympathetic nervous system; loss of vasoconstrictor tone. Results in massive vasodilation, leading to pooling of blood in vessels, tissue hypoperfusion, ultimately impaired cellular metabolism. Inability to regulate body temperature (resulting in heat loss) Poikilothermia- taking on temperature of environment (cool or warm)

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