NURS 3664 Lecture Notes - Lecture 9: Acute Respiratory Distress Syndrome, Disseminated Intravascular Coagulation, Cardiopulmonary Bypass
Document Summary
Ards is a sudden progressive form of acute respiratory failure. Alveolar capillary membrane becomes damaged and more permeable to intravascular fluid. B,interstitial edema occurs with increased flow of fluid into the interstitial space. C,alveolar edema occurs when fluid crosses the blood-gas barrier. Patients who have both gram-negative septic shock and ards have a mortality rate of 70% to 90%. Aspiration of gastric content or other substances. Transfusion related lung injury (eg: multiple blood transfusions) Develops from a variety of direct or indirect lung injuries. Exact cause for damage to alveolar-capillary membrane not known. Pathophysiologic changes of ards thought to be due to stimulation of inflammatory and immune systems. Direct lung injury may cause ards, or ards may develop because of the systemic inflammatory response syndrome (sirs) Ards may also develop as a consequence of multiple organ dysfunction syndrome (mods) Neutrophils are attracted and release mediators, producing changes in lungs.
