ANSC 3316 Lecture Notes - Lecture 7: Gluconeogenesis, Growth Factor, Epiphyseal Plate
Document Summary
Influence of hormones of fat, bone, muscle: anabolic stimulates develops of tissues, catabolic inhibits growth or stimulates breakdown, proliferation cell division, differentiation cells gain function that is different than parent cell. Hormones of the somatotropic axis: srif somatostatin. Inhibits grf-induced gh intermittently to give pulses of gh. Released in a wave-like fashion (pulse is elongated) Decreased srif increase in baseline growth hormone and increase in size of each pulse. Increased srif decrease in grf-stimulated gh release. + no change in baseline gh: grf growth hormone-releasing factor. Active portion of the molecule = amino acids 1-29. Molecules become inactive after amino acids 1-3 break down/are metabolized. Affects growth hormone directly at pituitary gland, but primarily has its affects indirectly through somatostatin. Decrease in grf decrease in pulsatile nature. Increase in grf increase in growth hormone release: if a hormone has a direct affect on the pituitary gland, there will be receptors on the gland for that hormone, gh growth hormone.
