NUR 3145 Lecture Notes - Lecture 2: Abdominal Pain, Sedation, Muscle Weakness
Document Summary
Greatest bulk of body fluid is water. Intracellular fluid (icf): water that is inside the cells: 2/3 of total body water. Extracellular fluid (ecf): remaining body fluid outside of cells: 1/3 of total body water. Measure of the number of dissolved particles or solutes in. 1kg (1l) of water: three solutes determine osmolality: sodium, glucose, & urea, normal osmolality: 275 295 milliosmoles per kg (mosm/kg) Ability of a solution to cause change in water movement across membrane due to osmotic forces: isotonic. Has tonicity of normal plasma (reference point: hypertonic greater concentration of solution than plasma, hypotonic lesser concentration of solutes than plasma. Water moves from areas of low solute concentration to areas of high solute concentration. Overall fluid balance is regulated primarily by hormones acting upon the kidneys. Water moves from areas of low solute concentration to areas of high concentration. Hypothalamus senses that ecf is hypertonic and triggers thirst.
